ThuliumV1, Main, Exploration, bibRecord, 003479

Thulium 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrakis(methylene phosphonate) as a 23Na shift reagent for the in vivo rat liver

Identifieur interne : 003479 ( Main/Exploration ); précédent : 003478; suivant : 003480

Thulium 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrakis(methylene phosphonate) as a 23Na shift reagent for the in vivo rat liver

Auteurs : N. Bansal [États-Unis] ; M. J. Germann [États-Unis] ; V. Seshan [États-Unis] ; G. T. Iii Shires ; C. R. Malloy [États-Unis] ; A. D. Sherry [États-Unis]

Source :

Biochemistry : (Easton) [ 0006-2960 ] ; 1993.

RBID : Pascal:93-0581015

Descripteurs français

KwdFr :
- Animaux, Composés organiques du phosphore, Composés organométalliques, Espace extracellulaire (physiologie), Foie (physiologie), Imagerie par résonance magnétique, Liquide intracellulaire (physiologie), Mâle, Phosphore, Potentiels de membrane, Pression sanguine, Rat Sprague-Dawley, Rats, Sodium (métabolisme), Spectroscopie par résonance magnétique (), Thulium.
MESH :
- métabolisme : Sodium.
- physiologie : Espace extracellulaire, Foie, Liquide intracellulaire.
Pascal (Inist)
- Animaux, Composés organiques du phosphore, Composés organométalliques, Imagerie par résonance magnétique, Mâle, Phosphore, Potentiels de membrane, Pression sanguine, Rat Sprague-Dawley, Rats, Réactif déplacement, Spectrométrie RMN, Sodium Ion, Gradient, Spectroscopie par résonance magnétique, Temps relaxation, Foie, Rat, In vivo, Thulium.

English descriptors

KwdEn :
- Animals, Blood Pressure, Extracellular Space (physiology), Gradient, In vivo, Intracellular Fluid (physiology), Liver, Liver (physiology), Magnetic Resonance Imaging, Magnetic Resonance Spectroscopy (methods), Male, Membrane Potentials, NMR spectrometry, Organometallic Compounds, Organophosphorus Compounds, Phosphorus, Rat, Rats, Rats, Sprague-Dawley, Relaxation time, Shift reagent, Sodium (metabolism), Sodium Ions, Thulium.
MESH :
- chemical , metabolism : Sodium.
- chemical : Organometallic Compounds, Organophosphorus Compounds, Phosphorus, Thulium.
- methods : Magnetic Resonance Spectroscopy.
- physiology : Extracellular Space, Intracellular Fluid, Liver.
- Animals, Blood Pressure, Magnetic Resonance Imaging, Male, Membrane Potentials, Rats, Rats, Sprague-Dawley.

Abstract

The use of thulium 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrakis(methylene phosphonate (TmDOTP^5-) as an in vivo ²³Na NMR shift reagent for rat liver was evaluated by collecting interleaved ²³Na and ³¹P spectra. Infusion of 80 mM TmDOTP^5- without added Ca²⁺ produced baseline-resolved peaks from intra- and extracellular sodium without producing any changes in phosphate metabolite resonances or intracellular pH. Several key physiological parameters measured in parallel groups of animals confirmed that liver physiology is largely unaffected by this shift reagent

Affiliations:

États-Unis

Le document en format XML

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Na shift reagent for the in vivo rat liver</title>
<author><name sortKey="Bansal, N" sort="Bansal, N" uniqKey="Bansal N" first="N." last="Bansal">N. Bansal</name>
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<s2>Dallas TX 75235-9085</s2>
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<date when="1993">1993</date>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Thulium 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrakis(methylene phosphonate) as a <sup>23</sup>
Na shift reagent for the in vivo rat liver</title>
<author><name sortKey="Bansal, N" sort="Bansal, N" uniqKey="Bansal N" first="N." last="Bansal">N. Bansal</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Univ. Texas Southwestern medical cent., Mary Nell Ralph B. Rogers magnetic resonance cent., dep. radiology</s1>
<s2>Dallas TX 75235-9085</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
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<country>États-Unis</country>
<wicri:noRegion>Dallas TX 75235-9085</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Germann, M J" sort="Germann, M J" uniqKey="Germann M" first="M. J." last="Germann">M. J. Germann</name>
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<s2>Dallas TX 75235-9085</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Dallas TX 75235-9085</wicri:noRegion>
</affiliation>
</author>
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<s2>Dallas TX 75235-9085</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Dallas TX 75235-9085</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Shires, G T Iii" sort="Shires, G T Iii" uniqKey="Shires G" first="G. T. Iii" last="Shires">G. T. Iii Shires</name>
</author>
<author><name sortKey="Malloy, C R" sort="Malloy, C R" uniqKey="Malloy C" first="C. R." last="Malloy">C. R. Malloy</name>
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<s2>Dallas TX 75235-9085</s2>
<s3>USA</s3>
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<country>États-Unis</country>
<wicri:noRegion>Dallas TX 75235-9085</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Sherry, A D" sort="Sherry, A D" uniqKey="Sherry A" first="A. D." last="Sherry">A. D. Sherry</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Univ. Texas Southwestern medical cent., Mary Nell Ralph B. Rogers magnetic resonance cent., dep. radiology</s1>
<s2>Dallas TX 75235-9085</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<wicri:noRegion>Dallas TX 75235-9085</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Biochemistry : (Easton)</title>
<title level="j" type="abbreviated">Biochemistry : (Easton)</title>
<idno type="ISSN">0006-2960</idno>
<imprint><date when="1993">1993</date>
</imprint>
</series>
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<seriesStmt><title level="j" type="main">Biochemistry : (Easton)</title>
<title level="j" type="abbreviated">Biochemistry : (Easton)</title>
<idno type="ISSN">0006-2960</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals</term>
<term>Blood Pressure</term>
<term>Extracellular Space (physiology)</term>
<term>Gradient</term>
<term>In vivo</term>
<term>Intracellular Fluid (physiology)</term>
<term>Liver</term>
<term>Liver (physiology)</term>
<term>Magnetic Resonance Imaging</term>
<term>Magnetic Resonance Spectroscopy (methods)</term>
<term>Male</term>
<term>Membrane Potentials</term>
<term>NMR spectrometry</term>
<term>Organometallic Compounds</term>
<term>Organophosphorus Compounds</term>
<term>Phosphorus</term>
<term>Rat</term>
<term>Rats</term>
<term>Rats, Sprague-Dawley</term>
<term>Relaxation time</term>
<term>Shift reagent</term>
<term>Sodium (metabolism)</term>
<term>Sodium Ions</term>
<term>Thulium</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Animaux</term>
<term>Composés organiques du phosphore</term>
<term>Composés organométalliques</term>
<term>Espace extracellulaire (physiologie)</term>
<term>Foie (physiologie)</term>
<term>Imagerie par résonance magnétique</term>
<term>Liquide intracellulaire (physiologie)</term>
<term>Mâle</term>
<term>Phosphore</term>
<term>Potentiels de membrane</term>
<term>Pression sanguine</term>
<term>Rat Sprague-Dawley</term>
<term>Rats</term>
<term>Sodium (métabolisme)</term>
<term>Spectroscopie par résonance magnétique ()</term>
<term>Thulium</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Sodium</term>
</keywords>
<keywords scheme="MESH" type="chemical" xml:lang="en"><term>Organometallic Compounds</term>
<term>Organophosphorus Compounds</term>
<term>Phosphorus</term>
<term>Thulium</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Magnetic Resonance Spectroscopy</term>
</keywords>
<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Sodium</term>
</keywords>
<keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Espace extracellulaire</term>
<term>Foie</term>
<term>Liquide intracellulaire</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Extracellular Space</term>
<term>Intracellular Fluid</term>
<term>Liver</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Blood Pressure</term>
<term>Magnetic Resonance Imaging</term>
<term>Male</term>
<term>Membrane Potentials</term>
<term>Rats</term>
<term>Rats, Sprague-Dawley</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Animaux</term>
<term>Composés organiques du phosphore</term>
<term>Composés organométalliques</term>
<term>Imagerie par résonance magnétique</term>
<term>Mâle</term>
<term>Phosphore</term>
<term>Potentiels de membrane</term>
<term>Pression sanguine</term>
<term>Rat Sprague-Dawley</term>
<term>Rats</term>
<term>Réactif déplacement</term>
<term>Spectrométrie RMN</term>
<term>Sodium Ion</term>
<term>Gradient</term>
<term>Spectroscopie par résonance magnétique</term>
<term>Temps relaxation</term>
<term>Foie</term>
<term>Rat</term>
<term>In vivo</term>
<term>Thulium</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">The use of thulium 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrakis(methylene phosphonate (TmDOTP<sup>5-</sup>
) as an in vivo <sup>23</sup>
Na NMR shift reagent for rat liver was evaluated by collecting interleaved <sup>23</sup>
Na and <sup>31</sup>
P spectra. Infusion of 80 mM TmDOTP<sup>5-</sup>
 without added Ca<sup>2+</sup>
 produced baseline-resolved peaks from intra- and extracellular sodium without producing any changes in phosphate metabolite resonances or intracellular pH. Several key physiological parameters measured in parallel groups of animals confirmed that liver physiology is largely unaffected by this shift reagent</div>
</front>
</TEI>
<affiliations><list><country><li>États-Unis</li>
</country>
</list>
<tree><noCountry><name sortKey="Shires, G T Iii" sort="Shires, G T Iii" uniqKey="Shires G" first="G. T. Iii" last="Shires">G. T. Iii Shires</name>
</noCountry>
<country name="États-Unis"><noRegion><name sortKey="Bansal, N" sort="Bansal, N" uniqKey="Bansal N" first="N." last="Bansal">N. Bansal</name>
</noRegion>
<name sortKey="Germann, M J" sort="Germann, M J" uniqKey="Germann M" first="M. J." last="Germann">M. J. Germann</name>
<name sortKey="Malloy, C R" sort="Malloy, C R" uniqKey="Malloy C" first="C. R." last="Malloy">C. R. Malloy</name>
<name sortKey="Seshan, V" sort="Seshan, V" uniqKey="Seshan V" first="V." last="Seshan">V. Seshan</name>
<name sortKey="Sherry, A D" sort="Sherry, A D" uniqKey="Sherry A" first="A. D." last="Sherry">A. D. Sherry</name>
</country>
</tree>
</affiliations>
</record>

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Serveur d'exploration sur le thulium

Thulium 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrakis(methylene phosphonate) as a 23Na shift reagent for the in vivo rat liver

Thulium 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrakis(methylene phosphonate) as a 23Na shift reagent for the in vivo rat liver

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

	Serveur d'exploration sur le thulium
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